miRNA regulation of cytokine genes.

نویسندگان

  • Ananthi J Asirvatham
  • William J Magner
  • Thomas B Tomasi
چکیده

In this review we discuss specific examples of regulation of cytokine genes and focus on a new mechanism involving post-transcriptional regulation via miRNAs. The post-transcriptional regulation of cytokine genes via the destabilizing activity of AU-rich elements [AREs] and miRNAs is a pre-requisite for regulating the half-life of many cytokines and achieving the temporal and spatial distributions required for regulation of these genes.

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عنوان ژورنال:
  • Cytokine

دوره 45 2  شماره 

صفحات  -

تاریخ انتشار 2009